Modern safety reporting in a legacy world – How cubeSAFETY compares, according to CRScube’s COO

With pharmacovigilance teams under increasing pressure to move faster, stay compliant, and do more with less, choosing the right safety system has never been more critical. We spoke with Ducksang (David) Im, Chief Operations Officer at CRScube, to discuss how cubeSAFETY compares to established players in the market, and why many organisations are rethinking legacy solutions. 

David, when organisations look at safety systems, who are they typically comparing cubeSAFETY against?

Most evaluations include long-established platforms like Oracle Argus, ArisGlobal LifeSphere, and Veeva Vault Safety. These systems are well known and widely used, particularly in large organisations.

So why would a company choose cubeSAFETY over these established competitors?

Legacy systems are undeniably powerful, but they’re often over-engineered and slow to deploy. cubeSAFETY is a modern, cloud-native platform designed specifically for flexibility and efficiency. We offer the same level of regulatory compliance as the “big three,” but with far greater agility, faster implementation, and a much more intuitive user experience.

Who is cubeSAFETY designed for?

The platform is highly scalable. It works equally well for emerging biotechs that need to move quickly, as for mid-to-large CROs managing multiple sponsor studies in parallel. The key is flexibility without compromising robustness.

From your perspective, what should sponsors and CROs prioritize when selecting a safety solution?

Two things above all else: regulatory assurance and user efficiency. First, the system must have a proven track record of accurate, error-free submissions to authorities like the FDA and EMA. Second, usability matters more than people often realize; intuitive interfaces reduce training time and significantly lower the risk of data entry errors. 

What would you say are the top differentiators of cubeSAFETY?

There are five that consistently stand out:

1. Ultra-Fast Implementation – We can go from contract to go-live in under two weeks, compared to months with legacy platforms.

2. Advanced AI Capabilities – AI-driven MedDRA coding, automated narrative generation, and intelligent CIOMS import dramatically reduce manual workload.

3. Seamless EDC Integration – Real-time data flow from clinical to safety eliminates reconciliation challenges, especially relevant now regulatory agencies require electronic submission for premarketing reporting.

4. Global Submission Readiness – Built-in validation rules ensure smooth submissions to global regulatory authorities.

5. Cost-Effective Scalability – A SaaS model that delivers enterprise-grade performance without enterprise-level overhead.

Looking ahead, how do you see the future of safety reporting evolving?

Safety reporting is moving beyond simple adverse event collection. The future lies in intelligent risk detection and frictionless data capture. At CRScube, we’re evolving cubeSAFETY to proactively identify safety signals across portfolios using AI, while also making data entry faster and more accurate. The goal is to free safety experts from administrative burden so they can focus on what truly matters: analysis and decision-making.

Legacy systems had their time, but pharmacovigilance is entering a new era. If you’re looking for a faster, smarter, and more flexible approach to safety reporting, cubeSAFETY may be the right fit.